Personalized therapy has revolutionized our approach to breast cancer (BC). Patient selection strategies and new biomarkers are the basis for increasingly complex diagnostic and therapeutic algorithms. In this short review, we discuss recent developments in breast oncology, focusing on controversial topics with relevance for clinical practice.

中文翻译：

---

乳腺癌系统治疗中的开放性问题和争议。

个性化治疗彻底改变了我们治疗乳腺癌 (BC) 的方法。患者选择策略和新的生物标志物是日益复杂的诊断和治疗算法的基础。在这篇简短的综述中，我们讨论了乳腺肿瘤学的最新发展，重点关注与临床实践相关的有争议的话题。