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Do oxytocin neurones affect feeding?
Journal of Neuroendocrinology ( IF 3.3 ) Pub Date : 2021-08-23 , DOI: 10.1111/jne.13035
Amy A Worth 1 , Simon M Luckman 1
Affiliation  

There has been a long history of research on the effects of oxytocin on feeding behaviour. The classic-held view is that the neurohormone is anorexigenic at least in rodents, although the data for humans are not so clear cut. Likewise, a physiological role for oxytocin is disputed. Thus, although pharmacological, anatomical and physiological data suggest oxytocin may have a function in satiety signalling, this view is not supported by the latest research using the genetic recording and manipulation of oxytocin neurones. Here, we avoid a discussion of the pharmacological effects of oxytocin and examine evidence, from both sides of the argument, concerning whether the endogenous oxytocin system has a role in the regulation of normal feeding.

中文翻译:

催产素神经元会影响喂养吗?

关于催产素对喂养行为的影响的研究历史悠久。经典的观点是神经激素至少在啮齿动物中是厌食的,尽管人类的数据并不那么明确。同样,催产素的生理作用也存在争议。因此,尽管药理学、解剖学和生理学数据表明催产素可能在饱腹感信号中发挥作用,但使用催产素神经元的遗传记录和操纵的最新研究并不支持这一观点。在这里,我们避免讨论催产素的药理作用,并从争论的双方检查关于内源性催产素系统是否在正常喂养调节中起作用的证据。
更新日期:2021-08-23
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