Safe-by-Design (SbD) has been put forward as a concept to assure that only safe nanomaterials will reach the market and that safety aspects have already been considered in a very early stage of the innovation process. In practice, several laboratory test have been proposed to screen newly developed nanomaterials and nano-enabled products to assess their hazardous nature. These tests need to have sufficient predictive power for possible adverse effects on human health, not only due to acute (peak) exposures, but also for long-term (low dose) exposures as these materials may accumulate over time in organs and tissues.

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安全设计 (SbD) 和纳米技术：一个谨慎讨论的话题？

安全设计 (SbD) 已被提出作为一个概念，以确保只有安全的纳米材料才能进入市场，并且在创新过程的早期阶段就已经考虑了安全问题。在实践中，已经提出了几个实验室测试来筛选新开发的纳米材料和纳米产品，以评估它们的危险性。这些测试需要对人类健康可能产生的不利影响具有足够的预测能力，不仅是由于急性（峰值）暴露，还包括长期（低剂量）暴露，因为这些材料可能会随着时间的推移在器官和组织中积累。