当前位置: X-MOL 学术Macromolecules › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Solvent-Free Three-Dimensional Printing of Biodegradable Elastomers Using Liquid Macrophotoinitiators
Macromolecules ( IF 5.1 ) Pub Date : 2021-08-23 , DOI: 10.1021/acs.macromol.1c00856
Matthias Sandmeier 1 , Nevena Paunović 1 , Riccardo Conti 2 , Leopold Hofmann 1 , Jieping Wang 2 , Zhi Luo 1 , Kunal Masania 3 , Na Wu 4 , Nicole Kleger 3 , Fergal Brian Coulter 3 , André R. Studart 3 , Hansjörg Grützmacher 2 , Jean-Christophe Leroux 1 , Yinyin Bao 1
Affiliation  

Vat photopolymerization 3D printing provides new opportunities for the fabrication of tissue scaffolds and medical devices. However, for the manufacturing of biodegradable elastomers, it usually requires the use of organic solvents to dissolve the solid photoinitators and achieve low resin viscosity, making this process environmentally unfriendly and not optimal for biomedical applications. Here, we report solvent-free 3D printing of biodegradable elastomers by digital light processing with well-defined photoinitiator–polymer conjugates. Being in liquid state at room temperature, the macrophotoinitiators enabled high-quality 3D printing in the absence of any organic solvents that are usually used in digital light 3D printing. This allowed the systematic investigation of structure–property relationships of 3D-printed biodegradable elastomers without the interference from reactive diluents. The developed macrophotoinitiators were compatible with various photopolymers and could be applied for solvent-free fabrication of biodegradable shape-memory devices. This work offers new perspectives for the solvent-free additive manufacturing of bioresorbable medical implants and other functional devices.

中文翻译:

使用液体宏观光引发剂的可生物降解弹性体的无溶剂三维打印

还原光聚合 3D 打印为组织支架和医疗器械的制造提供了新的机会。然而,对于可生物降解弹性体的制造,通常需要使用有机溶剂来溶解固体光引发剂并实现低树脂粘度,这使得该过程对环境不友好且不适合生物医学应用。在这里,我们报告了通过数字光处理与明确定义的光引发剂 - 聚合物共轭物的无溶剂 3D 打印可生物降解弹性体。在室温下处于液态,宏观光引发剂能够在没有任何通常用于数字光 3D 打印的有机溶剂的情况下进行高质量的 3D 打印。这使得系统研究 3D 打印的可生物降解弹性体的结构-性能关系成为可能,而不受反应性稀释剂的干扰。开发的宏观光引发剂与各种光聚合物兼容,可用于无溶剂制造可生物降解的形状记忆器件。这项工作为生物可吸收医疗植入物和其他功能设备的无溶剂增材制造提供了新的视角。
更新日期:2021-09-14
down
wechat
bug