We present an efficient and intensified single-reactor tandem process accessing a library of secondary furan diamines from HMF. The process comprises two in situ consecutive steps: (1) aerobic oxidation of HMF to DFF, and (2) reductive amination of DFF to diamines. The reactor was operated using a mechanical mixture of 5%Ru/C + 5%Pd/C catalysts with more than 87% overall yield of diamines. With these results, a bifunctional (Ru + Pd)/C catalyst was engineered with comparable results to the mechanical mixture.

中文翻译：

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5-羟甲基糠醛合成呋喃二胺的单反应器串联氧化-胺化工艺

我们提出了一种高效且强化的单反应器串联工艺，可访问来自 HMF 的仲呋喃二胺库。该过程包括两个原位连续步骤：(1) HMF 有氧氧化成 DFF，和 (2) DFF 还原胺化成二胺。使用 5% Ru/C + 5% Pd/C 催化剂的机械混合物操作反应器，二胺的总产率超过 87%。根据这些结果，设计了一种双功能 (Ru + Pd)/C 催化剂，其结果与机械混合物相当。