Proper placental development is pivotal to ensure healthy pregnancy outcomes. Among the multiple cellular mechanisms involved in the orchestration of this process, little is known on the role of alternative splicing events in the modulation of trophoblast cell biology. Here, we evaluated the expression of the alternative splicing regulator Rbfox2 in the pre- and post-placentation period in mouse pregnancies in both healthy and pathological settings.

中文翻译：

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胎盘发育过程中选择性剪接调节因子 Rbfox2 的表达在先兆子痫小鼠模型中受到差异调节

适当的胎盘发育对于确保健康的妊娠结果至关重要。在参与该过程协调的多种细胞机制中，关于选择性剪接事件在滋养层细胞生物学调节中的作用知之甚少。在这里，我们评估了替代剪接调节因子 Rbfox2 在健康和病理环境下小鼠妊娠前后胎盘的表达。