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An update on novel approaches for diagnosis and treatment of SARS-CoV-2 infection
Cell and Bioscience ( IF 6.1 ) Pub Date : 2021-08-22 , DOI: 10.1186/s13578-021-00674-6
Azadeh Safarchi 1 , Shadma Fatima 1, 2 , Zahra Ayati 3, 4 , Fatemeh Vafaee 1, 5
Affiliation  

The ongoing pandemic of coronavirus disease 2019 (COVID-19) has made a serious public health and economic crisis worldwide which united global efforts to develop rapid, precise, and cost-efficient diagnostics, vaccines, and therapeutics. Numerous multi-disciplinary studies and techniques have been designed to investigate and develop various approaches to help frontline health workers, policymakers, and populations to overcome the disease. While these techniques have been reviewed within individual disciplines, it is now timely to provide a cross-disciplinary overview of novel diagnostic and therapeutic approaches summarizing complementary efforts across multiple fields of research and technology. Accordingly, we reviewed and summarized various advanced novel approaches used for diagnosis and treatment of COVID-19 to help researchers across diverse disciplines on their prioritization of resources for research and development and to give them better a picture of the latest techniques. These include artificial intelligence, nano-based, CRISPR-based, and mass spectrometry technologies as well as neutralizing factors and traditional medicines. We also reviewed new approaches for vaccine development and developed a dashboard to provide frequent updates on the current and future approved vaccines.

中文翻译:

SARS-CoV-2 感染诊断和治疗新方法的最新进展

2019 年冠状病毒病 (COVID-19) 的持续大流行在全球范围内造成了严重的公共卫生和经济危机,全球齐心协力开发快速、精确且具有成本效益的诊断方法、疫苗和治疗方法。许多多学科研究和技术旨在调查和开发各种方法来帮助一线卫生工作者、政策制定者和民众战胜这种疾病。虽然这些技术已经在各个学科内进行了审查,但现在是时候对新颖的诊断和治疗方法进行跨学科概述,总结多个研究和技术领域的互补努力。因此,我们回顾并总结了用于诊断和治疗 COVID-19 的各种先进新方法,以帮助不同学科的研究人员确定研发资源的优先顺序,并让他们更好地了解最新技术。其中包括人工智能、纳米技术、CRISPR技术和质谱技术以及中和因子和传统药物。我们还审查了疫苗开发的新方法,并开发了一个仪表板,以提供当前和未来批准的疫苗的频繁更新。
更新日期:2021-08-23
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