Mechanisms discovered to drive increased glucose metabolism in cancer cells are found to be similar to those in viral-infected cells. In this mini review, we summarize the major pathways by which the sugar analog, 2-Deoxy-d-glucose, has been shown to exploit increased glucose metabolism in cancer and how this information applies to viral-infected cells. Moreover, we highlight the relevance of these findings to the emergency approval of 2-Deoxy-d-glucose in India to be used against SARS-CoV-2, the virus responsible for COVID-19.

中文翻译：

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2-脱氧-d-葡萄糖利用癌症和病毒感染细胞中葡萄糖代谢的增加：与其在印度用于对抗 SARS-CoV-2 的相关性

发现癌细胞中葡萄糖代谢增加的机制与病毒感染细胞中的机制相似。在这篇小综述中，我们总结了糖类似物 2-脱氧-d-葡萄糖已被证明利用癌症中葡萄糖代谢增加的主要途径，以及这些信息如何应用于病毒感染的细胞。此外，我们强调这些发现与印度紧急批准 2-脱氧-d-葡萄糖用于对抗 SARS-CoV-2（导致 COVID-19 的病毒）的相关性。