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Bio-corrosion behavior, antibacterial property and interaction with osteoblast of laser in-situ fabricated Ti–Si–Cu coatings on Ti–6Al–4V alloy
Biomedical Materials ( IF 3.9 ) Pub Date : 2021-09-03 , DOI: 10.1088/1748-605x/ac1f9d
Jingzhu Duan 1 , Juncai Wang 2 , Yu Di 3 , Yuling Yang 4 , Yang Yang 3
Affiliation  

Ti–Si–xCu coatings (TS-xC, x = 5, 10 and 15 wt.%) with advanced bio-corrosion resistance, excellent antibacterial property and biocompatibility were laser cladded on Ti–6Al–4V (TAV) substrate which is widely used as endosseous implants. The bio-corrosion resistance of the TAV substrate was improved due to the presence of Ti5Si3 and TiCu phases in the coatings. The addition of Cu in the precursor contributes to the improvement of the antibacterial property of TAV substrate. Meanwhile, induced normal cytoskeleton, well-developed focal adhesion contacts, significant higher cell attachment and proliferation rate were observed for the TS-xC coated samples due to the formation of micro-textured morphology and presence of new phases. The bio-corrosion resistance and antibacterial property depend on Cu content addition in the TS-xC precursor. The results provide a way to fabricate such multiple functional biocoating that would improve the bio-corrosion resistance, antibacterial performance and biocompatibility of TAV.



中文翻译:

Ti-6Al-4V合金激光原位制备Ti-Si-Cu涂层的生物腐蚀行为、抗菌性能及与成骨细胞的相互作用

在 Ti-6Al-4V (TAV) 基材上激光熔覆具有先进的生物腐蚀性能、优异的抗菌性能和生物相容性的Ti-Si- x Cu 涂层(TS- x C,x = 5、10 和 15 wt.%)广泛用作骨内植入物。由于涂层中存在 Ti 5 Si 3和 TiCu 相,TAV 基材的耐生物腐蚀性能得到改善。在前驱体中添加Cu有助于提高TAV底物的抗菌性能。同时,对于 TS- x,观察到诱导正常的细胞骨架、发育良好的粘着斑接触、显着更高的细胞粘附和增殖率。由于微纹理形态的形成和新相的存在,C 涂层样品。生物腐蚀性能和抗菌性能取决于 TS - x C 前驱体中 Cu 含量的添加。该结果提供了一种制造这种多功能生物涂层的方法,该涂层将提高 TAV 的生物耐腐蚀性、抗菌性能和生物相容性。

更新日期:2021-09-03
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