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Altered stress granule disassembly: links to neurodegenerative disease?
Trends in Neurosciences ( IF 14.6 ) Pub Date : 2021-08-21 , DOI: 10.1016/j.tins.2021.08.001
Alicia Dubinski 1 , Christine Vande Velde 1
Affiliation  

A recent study by Gwon et al. identified context-specific ubiquitination of G3BP1 as critical for stress granule disassembly via VCP and the adaptor FAF2. This study provides new insights into stress granule dynamics, with potential implications for neurodegenerative disease.



中文翻译:

改变应力颗粒分解:与神经退行性疾病的联系?

Gwon等人最近的一项研究确定 G3BP1 的上下文特定泛素化对于通过 VCP 和适配器 FAF2 分解应力颗粒至关重要。这项研究提供了对压力颗粒动力学的新见解,对神经退行性疾病具有潜在影响。

更新日期:2021-09-28
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