Decades of research on trauma patients have shown that a post-traumatic stress disorder (PTSD) diagnosis does not always cover the full spectrum of symptoms after severe trauma. Complex PTSD (CPTSD) was recently introduced in the International Classification of Diseases 11th Revision. There have been no published studies on CPTSD in the South Asian region to date. The objective of this study was to evaluate CPTSD in a sample of trauma patients in Nepal. We also examined quality of life (QOL) and mental health comorbidities and their association with CPTSD caseness. One hundred patients with a history of trauma who visited the outpatient psychiatry clinic at a hospital in Kathmandu from 2017 to 2018 were assessed. The Composite International Diagnostic Interview Version 2.1 was used to evaluate PTSD, major depressive disorder, and generalized anxiety disorder (GAD). Disturbance of self-organization symptoms from the Structured Interview for Disorders of Extreme Stress (SIDES) together with the PTSD diagnosis was used to confirm CPTSD caseness. The World Health Organization (WHO) QOL Scale Brief Version (WHOQOL-BREF) was used to assess QOL in four domains. Among the 83 patients who had PTSD, 42 also had CPTSD. CPTSD was significantly associated with major depressive disorder, GAD, female gender, and lower QOL in all four domains. CPTSD was prevalent among these patients. Having CPTSD was significantly associated with worse outcomes in terms of QOL and comorbid mental disorders, even with similar trauma. There is a need to explore CPTSD symptoms and to address trauma patients with CPTSD in this region.

对创伤患者的数十年研究表明，创伤后应激障碍 (PTSD) 诊断并不总是涵盖严重创伤后的所有症状。最近在国际疾病分类第 11 版中引入了复杂 PTSD (CPTSD)。迄今为止，尚未在南亚地区发表关于 CPTSD 的研究。本研究的目的是评估尼泊尔创伤患者样本中的 CPTSD。我们还检查了生活质量 (QOL) 和心理健康合并症及其与 CPTSD 病例的关联。对 2017 年至 2018 年在加德满都一家医院的精神科门诊就诊的 100 名有创伤史的患者进行了评估。综合国际诊断访谈 2.1 版用于评估 PTSD、重度抑郁症、和广泛性焦虑症（GAD）。来自极端压力障碍（SIDES）的结构化访谈的自组织症状紊乱与 PTSD 诊断一起用于确认 CPTSD 病例。世界卫生组织 (WHO) QOL 量表简要版本 (WHOQOL-BREF) 用于评估四个领域的 QOL。在 83 名患有 PTSD 的患者中，42 名也患有 CPTSD。CPTSD 与所有四个领域的重度抑郁症、GAD、女性和较低的 QOL 显着相关。CPTSD 在这些患者中普遍存在。即使有类似的创伤，CPTSD 与 QOL 和共存精神障碍方面的较差结果显着相关。有必要探索 CPTSD 症状并解决该地区的 CPTSD 创伤患者。来自极端压力障碍（SIDES）的结构化访谈的自组织症状紊乱与 PTSD 诊断一起用于确认 CPTSD 病例。世界卫生组织 (WHO) QOL 量表简要版本 (WHOQOL-BREF) 用于评估四个领域的 QOL。在 83 名患有 PTSD 的患者中，42 名也患有 CPTSD。CPTSD 与所有四个领域的重度抑郁症、GAD、女性和较低的 QOL 显着相关。CPTSD 在这些患者中普遍存在。即使有类似的创伤，CPTSD 与 QOL 和共存精神障碍方面的较差结果显着相关。有必要探索 CPTSD 症状并解决该地区的 CPTSD 创伤患者。来自极端压力障碍的结构化访谈 (SIDES) 的自组织症状紊乱与 PTSD 诊断一起用于确认 CPTSD 病例。世界卫生组织 (WHO) QOL 量表简要版本 (WHOQOL-BREF) 用于评估四个领域的 QOL。在 83 名患有 PTSD 的患者中，42 名也患有 CPTSD。CPTSD 与所有四个领域的重度抑郁症、GAD、女性和较低的 QOL 显着相关。CPTSD 在这些患者中普遍存在。即使有类似的创伤，CPTSD 与 QOL 和共存精神障碍方面的较差结果显着相关。有必要探索 CPTSD 症状并解决该地区的 CPTSD 创伤患者。