The present review summarizes the available knowledge concerning the action of curcumin, the best-known polyphenol among the rhizomes of Curcumas, on female reproductive processes and their dysfunctions. Curcumin affects a number of physiological processes, including female reproduction (puberty, reproductive aging, ovarian follicullogenesis and oogenesis, and fecundity). Curcumin can affect these processes via changes in the release and reception of pituitary and ovarian hormones, growth factors and cytokines. Furthermore, it can influence the response of ovarian cells to these substances and external environmental factors. Finally, curcumin can affect oxidative processes within the ovary and numerous intracellular signalling pathways related to ovarian cell proliferation and apoptosis. These effects suggest the applicability of curcumin for stimulation of female reproductive processes in vivo and in vitro, as well as for the prevention, mitigation, and treatment of various reproductive disorders from ovarian insufficiency and infertility to polycystic ovarian syndrome and ovarian cancer.

中文翻译：

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姜黄和姜黄素对女性生殖过程的影响

本综述总结了有关姜黄素（姜黄根茎中最著名的多酚）对女性生殖过程及其功能障碍的作用的现有知识。姜黄素影响许多生理过程，包括女性生殖（青春期、生殖衰老、卵巢卵泡发生和卵子发生以及生育力）。姜黄素可以通过改变垂体和卵巢激素、生长因子和细胞因子的释放和接收来影响这些过程。此外，它可以影响卵巢细胞对这些物质和外部环境因素的反应。最后，姜黄素可以影响卵巢内的氧化过程以及与卵巢细胞增殖和凋亡相关的许多细胞内信号通路。