Research question

What are the associations between endometriosis, pelvic pain symptoms, fatigue and sleep? Psychological health and quality of life in endometriosis patients with good versus bad quality of sleep were also examined.

Design

This matched pair case–control study included 123 consecutive endometriosis patients and 123 women without a history of endometriosis (matched to patients for age and body mass index). Endometriosis-related pelvic pain severity was rated on a 0–10 numerical rating scale. Fatigue was measured on a 1–5 Likert scale. Women also completed a set of self-report questionnaires for assessing sleep disturbances (Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale, Insomnia Severity Index), psychological health (Hospital Anxiety and Depression Scale) and quality of life (Short Form-12).

Results

Painful endometriosis had an impact on fatigue (P = 0.006; η²_p = 0.041) and sleep (P < 0.001; η²_p = 0.051). Women with painful endometriosis reported significantly greater fatigue, poorer quality of sleep, higher daytime sleepiness and more severe insomnia than women without significant pain symptoms and controls. Poorer quality of sleep among endometriosis patients was associated with greater fatigue (P < 0.001; η²_p = 0.130), poorer psychological health (P < 0.001; η²_p = 0.135), and lower quality of life (P < 0.001; η²_p = 0.240).

Conclusions

Pelvic pain (rather than endometriosis in itself) is associated with fatigue and sleep disturbances, with poor sleep having a detrimental impact on women's psychological health and quality of life.

中文翻译：

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子宫内膜异位症女性的睡眠障碍、疲劳和心理健康：配对病例对照研究

研究问题

子宫内膜异位症、盆腔疼痛症状、疲劳和睡眠之间有什么关联？还检查了睡眠质量好与坏的子宫内膜异位症患者的心理健康和生活质量。

设计

这项配对病例对照研究包括 123 名连续的子宫内膜异位症患者和 123 名没有子宫内膜异位症病史的女性（与患者的年龄和体重指数相匹配）。子宫内膜异位症相关的盆腔疼痛严重程度采用 0-10 数字评分量表进行评分。疲劳以 1-5 的李克特量表进行测量。女性还完成了一套自我报告问卷，用于评估睡眠障碍（匹兹堡睡眠质量指数、Epworth 嗜睡量表、失眠严重程度指数）、心理健康（医院焦虑和抑郁量表）和生活质量（Short Form-12）。

结果

疼痛的子宫内膜异位症对疲劳（P  = 0.006；η ² _p  = 0.041）和睡眠（P  < 0.001；η ² _p  = 0.051）有影响。与没有明显疼痛症状和对照组的女性相比，患有疼痛性子宫内膜异位症的女性报告的疲劳、睡眠质量差、白天嗜睡和失眠更严重。子宫内膜异位症患者睡眠质量较差与疲劳程度较高（P  < 0.001；η ² _p  =  0.130）、心理健康状况较差（P  < 0.001；η ² _p  = 0.135）和生活质量下降有关（P  < 0.001；η ² _p  = 0.240)。

结论

盆腔疼痛（而不是子宫内膜异位症本身）与疲劳和睡眠障碍有关，睡眠不佳会对女性的心理健康和生活质量产生不利影响。