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The Synthesis of Five-Membered N-Heterocycles by Cycloaddition of Nitroalkenes with (In)Organic Azides and Other 1,3-Dipoles
Synthesis ( IF 2.2 ) Pub Date : 2021-07-09 , DOI: 10.1055/a-1547-0196
Shandev Pookkandam Parambil 1, 2 , Santhini Pulikkal Veettil 1 , Wim Dehaen 1
Affiliation  

Cycloaddition reactions have emerged as rapid and powerful methods for constructing heterocycles and carbocycles. [3+2] Cyclo­additions of nitroalkenes with various 1,3-dipoles have been an interesting research area for many organic chemists. This review outlines the synthesis of N-substituted and NH-1,2,3-triazoles along with other five-membered N-heterocycles through cycloaddition reactions of nitro­alkenes.1 Introduction2 Synthesis of 1,2,3-Triazoles2.1 Synthesis of NH-1,2,3-Triazoles2.2 Synthesis of N-Substituted 1,2,3-Triazoles3 Synthesis of Pyrrolidines and Pyrroles4 Synthesis of Pyrazoles5 Conclusion

中文翻译:

硝基烯烃与(In)有机叠氮化物和其他 1,3-偶极子环加成合成五元 N-杂环

环加成反应已成为构建杂环和碳环的快速而有效的方法。[3+2] 具有各种 1,3-偶极子的硝基烯烃的环加成对许多有机化学家来说是一个有趣的研究领域。本综述概述了通过硝基烯烃的环加成反应合成 N-取代和 NH-1,2,3-三唑以及其他五元 N-杂环。1 引言 2 1,2,3-三唑的合成 2.1 NH 的合成-1,2,3-三唑2.2 N-取代1,2,3-三唑的合成3 吡咯烷和吡咯的合成4 吡唑的合成5 结论
更新日期:2021-08-20
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