The ontogeny programs are highly conserved across all vertebrates, although there are significant temporal variations in interspecies developmental processes. Changing the timing and rate of developmental processes could affect subsequent organogenesis profoundly and may also have been critical factors in evolutionary diversity. However, despite their potential importance, the cellular and molecular mechanisms that control interspecies differences in developmental timescale remain unclear. This review highlights recent advances in the experimental models to compare interspecies differences in neurodevelopmental processes, neurogenesis, and neuronal maturation and discusses the possible mechanisms that could generate species-specific timescales.

尽管种间发育过程存在显着的时间变化，但所有脊椎动物的个体发育程序都是高度保守的。改变发育过程的时间和速度可能会深刻影响随后的器官发生，也可能是进化多样性的关键因素。然而，尽管它们具有潜在的重要性，但在发育时间尺度上控制种间差异的细胞和分子机制仍不清楚。这篇综述强调了实验模型的最新进展，以比较神经发育过程、神经发生和神经元成熟的种间差异，并讨论了可能产生特定物种时间尺度的机制。