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Medical phenome of musicians: an investigation of health records collected on 9803 musically active individuals
Annals of the New York Academy of Sciences ( IF 4.1 ) Pub Date : 2021-08-19 , DOI: 10.1111/nyas.14671 Maria Niarchou 1 , George T Lin 2 , Miriam D Lense 3, 4 , Reyna L Gordon 1, 3, 4 , Lea K Davis 1, 5, 6, 7, 8
Annals of the New York Academy of Sciences ( IF 4.1 ) Pub Date : 2021-08-19 , DOI: 10.1111/nyas.14671 Maria Niarchou 1 , George T Lin 2 , Miriam D Lense 3, 4 , Reyna L Gordon 1, 3, 4 , Lea K Davis 1, 5, 6, 7, 8
Affiliation
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Previous studies suggest that musicians may be at higher risk for a set of medical problems; however, this literature has been limited by relatively small sample sizes, self-reports, and lack of controls. To address such limitations, we examined trends in the medical care of musicians in an Electronic Health Record database. On the basis of a collection of keywords and regular expressions in the patients’ clinical notes, we identified 9803 “musicians” that we matched for sex, median age (across the medical record), ethnicity, race, the length of record, and the number of visits with 49,015 controls. We fitted 1263 logistic regression models to determine whether the phenotype was correlated with musicianship. Two hundred fifty-seven phenotypes were more prevalent in musicians than controls after Bonferroni adjustment (P < 7.6 × 10–6), including diseases of the larynx and vocal cords (OR = 2.32 (95% CI: 2.25–2.40)), and hearing loss (OR = 1.36 (95% CI: 1.32–1.39)). Fifteen phenotypes were significantly more prevalent in controls than musicians, including coronary atherosclerosis (OR = 0.91 (95% CI: 0.89–0.94)). Although being a musician was related to many occupational health problems, we identified protective effects of musicianship in which certain disorders were less common in musicians than in controls, indicating that active musical engagement could have health benefits analogous to athletic engagement.
中文翻译：
音乐家的医学现象：对 9803 名音乐活跃个体的健康记录的调查
先前的研究表明，音乐家可能面临一系列医疗问题的更高风险；然而，该文献受到相对较小的样本量、自我报告和缺乏控制的限制。为了解决这些限制，我们在电子健康记录数据库中检查了音乐家医疗保健的趋势。根据患者临床记录中的关键字和正则表达式的集合，我们确定了 9803 位“音乐家”，我们根据性别、中位年龄（整个医疗记录）、种族、种族、记录长度和访问次数为 49,015 次控制。我们拟合了 1263 个逻辑回归模型来确定表型是否与音乐才能相关。在 Bonferroni 调整后，257 种表型在音乐家中比对照组更普遍（P <7.6 × 10 –6 )，包括喉部和声带疾病 (OR = 2.32 (95% CI: 2.25–2.40)) 和听力损失 (OR = 1.36 (95% CI: 1.32–1.39))。15 种表型在对照组中比音乐家更普遍，包括冠状动脉粥样硬化 (OR = 0.91 (95% CI: 0.89–0.94))。尽管成为音乐家与许多职业健康问题有关，但我们确定了音乐才能的保护作用，其中某些疾病在音乐家中不如在对照组中常见，这表明积极的音乐参与可能具有与运动参与类似的健康益处。
更新日期：2021-08-19
中文翻译：
音乐家的医学现象：对 9803 名音乐活跃个体的健康记录的调查
先前的研究表明，音乐家可能面临一系列医疗问题的更高风险；然而，该文献受到相对较小的样本量、自我报告和缺乏控制的限制。为了解决这些限制，我们在电子健康记录数据库中检查了音乐家医疗保健的趋势。根据患者临床记录中的关键字和正则表达式的集合，我们确定了 9803 位“音乐家”，我们根据性别、中位年龄（整个医疗记录）、种族、种族、记录长度和访问次数为 49,015 次控制。我们拟合了 1263 个逻辑回归模型来确定表型是否与音乐才能相关。在 Bonferroni 调整后，257 种表型在音乐家中比对照组更普遍（P <7.6 × 10 –6 )，包括喉部和声带疾病 (OR = 2.32 (95% CI: 2.25–2.40)) 和听力损失 (OR = 1.36 (95% CI: 1.32–1.39))。15 种表型在对照组中比音乐家更普遍，包括冠状动脉粥样硬化 (OR = 0.91 (95% CI: 0.89–0.94))。尽管成为音乐家与许多职业健康问题有关，但我们确定了音乐才能的保护作用，其中某些疾病在音乐家中不如在对照组中常见，这表明积极的音乐参与可能具有与运动参与类似的健康益处。
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