Titanium and its alloys have been widely used as orthopedic and dental implants. However, during practical use, wear debris and surface corrosion will cause the overproduction of reactive oxygen species leading to an inflammatory reaction, which has detrimental effects on osteogenesis around the titanium implants. To solve this problem, in this work, cerium modified titanium surface was constructed by plasma immersion ion implantation (PIII) technology. The mechanical property, corrosion resistance, antioxidant capability, and osteogenic properties of modified titanium were systematically studied. The results indicate that surface hardness and corrosion resistance of modified titanium are markedly improved and the reactive oxygen species level is reduced. Moreover, cell spreading, proliferation, alkaline phosphatase, and collagen secretion of rBMSCs on modified titanium surfaces are improved.

钛及其合金已广泛用作骨科和牙科植入物。然而，在实际使用过程中，磨屑和表面腐蚀会导致活性氧过量产生，导致炎症反应，对钛种植体周围的成骨产生不利影响。为了解决这个问题，在这项工作中，通过等离子体浸入离子注入（PIII）技术构建了铈改性的钛表面。系统研究了改性钛的力学性能、耐腐蚀性能、抗氧化能力和成骨性能。结果表明，改性钛的表面硬度和耐腐蚀性能显着提高，活性氧水平降低。此外，细胞扩散、增殖、碱性磷酸酶、