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Can anatomical feasibility studies drive neurosurgical procedures and reach patients faster than traditional translational research?
Neurosurgical Review ( IF 2.5 ) Pub Date : 2021-08-19 , DOI: 10.1007/s10143-021-01626-x
Joe Iwanaga 1, 2, 3 , Nicole A Boggio 1 , C J Bui 4 , Aaron S Dumont 1 , R Shane Tubbs 1, 2, 4, 5, 6, 7
Affiliation  

Often, surgical techniques are practiced and studied in the anatomy laboratory. Occasionally, new surgical methods are developed with cadaveric anatomical studies. Some cadaveric feasibility studies, if published, might go on to be used by surgeons from around the world for improved patient care. Herein, we review our experience with 37 published anatomical feasibility studies over an 18-year period (2002–2020) and analyze the literature for published examples of surgical application of these same anatomical studies. We found that, for cadaveric anatomical feasibility studies within 7 years of their publication date, approximately 22% will be used in neurosurgery with the clinical applications published. Of these studies awarded clinical citation within 7 years of publication, the median time to that citation was approximately 3.4 years. As the average time for translational research to reach patient care is 17 years, cadaveric anatomical studies in this series reached patient care much sooner than traditional translational research. Cadaveric anatomical studies, based on our experience, can drive neurosurgical procedures.



中文翻译:

与传统的转化研究相比,解剖可行性研究能否推动神经外科手术并更快地接触到患者?

通常,手术技术在解剖实验室中进行实践和研究。有时,通过尸体解剖学研究会开发出新的手术方法。一些尸体可行性研究如果发表,可能会继续被世界各地的外科医生用于改善患者护理。在此,我们回顾了我们在 18 年期间(2002-2020 年)发表的 37 项解剖可行性研究的经验,并分析了这些相同解剖研究的已发表外科应用示例的文献。我们发现,对于发表日期后 7 年内的尸体解剖可行性研究,大约 22% 将用于神经外科并发表临床应用。这些研究在发表后 7 年内获得临床引用,中位引用时间约为 3.4 年。由于转化研究达到患者护理的平均时间为 17 年,因此本系列中的尸体解剖研究比传统的转化研究更快地达到患者护理。根据我们的经验,尸体解剖学研究可以推动神经外科手术。

更新日期:2021-08-19
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