Introduction/aims

The hand is a sophisticated tool which allows humans to interact with the external world mainly via the sense of touch. Previous evidences demonstrated that electrical stimulations of the nerve trunks governing the hand are able to restore touch perception in transradial amputees. The aim of this study was to evaluate the neurological correlates of restored perception by the evaluation of network characteristics of the brain connectome via EEG recordings in amputees utilizing a fully sensorized bionic hand.

Methods

A 48-year-old female with a left wrist traumatic disarticulation incurred 23 years prior to the study was enrolled for 6 months, during which experimental sessions were randomized. The control group included 12 healthy subjects performing a similar protocol.

Results

Results showed that in both amputee and control group, a trend of SW in delta and beta 1 is recognizable (Delta and Beta 1 opposite spread) selectively in the hemisphere contralateral to the stimulus.

Discussion

Delta increases (less orderly network) while Beta 1 decreases (more ordered network). It could be seen as a sign of higher attention and concentration of subjects to understand the perception and this monolateral modulation is similar to the bilateral attention given to the mathematical task difficulty’s increment.

中文翻译：

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通过仿生神经内刺激恢复手指知觉的经桡动脉截肢者的脑网络调制

简介/目标

手是一种复杂的工具，它允许人类主要通过触觉与外部世界进行交互。先前的证据表明，控制手部的神经干的电刺激能够恢复经桡动脉截肢者的触觉。本研究的目的是通过使用完全感应仿生手的截肢者的脑电图记录评估大脑连接组的网络特征来评估恢复感知的神经学相关性。

方法

一名 48 岁女性在研究前 23 年发生左手腕外伤性脱节，被纳入 6 个月，在此期间随机进行实验。对照组包括执行类似方案的 12 名健康受试者。

结果

结果表明，在截肢者和对照组中，在刺激对侧的半球中，可以选择性地识别出 delta 和 beta 1 中的 SW 趋势（Delta 和 Beta 1 反向传播）。

讨论

Delta 增加（不太有序的网络），而 Beta 1 减少（更有序的网络）。可以将其视为对理解感知的更高注意力和集中度的标志，这种单边调制类似于对数学任务难度增加的双边注意力。