Previously obtained hydrochlorides of 1-[3,4-(R¹)₂-benzyl]-3,3-(R²)₂-6,7-(R³)₂-3,4-dihydroisoquinolines (R¹ = H, MeO, EtO; R² = Alk; R³ = MeO, EtO) and their benzo[f]-analogs proved to be water-soluble compounds. This advantage enabled additional biological testing of them for a number of activity types such as antiarrhythmic, hemostatic, anthelmintic, and larvicidal. All isoquinoline hydrochlorides were tested for antiarrhythmic activity (CaCl₂ model) with 7 of 13 compounds being active. The maximum antiarrhythmic index was 3.97. The obtained isoquinolines were predominantly coagulants (hemostatics) with respect to blood clotting. The most active compound increased blood coagulation by 46.6%. All compounds with anthelmintic activity exceeded the effect of pyrantel. The larvicidal (insecticidal) effect of the most active compound was comparable with that of diazinon.

先前获得的 1-[3,4-(R ¹ ) ₂ -苄基]-3,3-(R ² ) ₂ -6,7-(R ³ ) ₂ -3,4-二氢异喹啉的盐酸盐(R ¹ = H , MeO, EtO; R ² = Alk; R ³ = MeO, EtO) 和它们的苯并[ f ]-类似物被证明是水溶性化合物。这一优势使得可以对它们的多种活性类型进行额外的生物测试，例如抗心律失常、止血、驱虫和杀幼虫。测试了所有异喹啉盐酸盐的抗心律失常活性 (CaCl ₂模型），其中 13 种化合物中有 7 种具有活性。最大抗心律失常指数为 3.97。获得的异喹啉在凝血方面主要是凝血剂（止血剂）。最活跃的化合物使血液凝固增加了 46.6%。所有具有驱虫活性的化合物都超过了吡喃特的作用。最活性化合物的杀幼虫（杀虫）效果与二嗪农相当。