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Species of the Genus Teucrium L. as Sources of Active Pharmaceutical Substances with Antimicrobial, Anti-Inflammatory, and Radioprotective Activity (Review)
Pharmaceutical Chemistry Journal ( IF 0.8 ) Pub Date : 2021-08-13 , DOI: 10.1007/s11094-021-02443-8
I. G. Medvetskaya 1 , I. V. Popov 1 , A. I. Medvetskii 1 , O. I. Popova 1
Affiliation  

Literature data on the contents of secondary metabolite complexes in plants of the genus Teucrium L. (germander) including essential oil, phenolic compounds (flavonoids, iridoids), diterpenoids, and hydroxycinnamic acids are summarized. The spectrum of biological activity of these compounds is described both under normal conditions and in various pathological states. The need to determine the main quality indicators and develop methods for standardization of plant raw materials indicates further in-depth research of Teucrium species that can be sources of pharmaceutical substances for obtaining new drugs with antibacterial, antimicrobial, and radioprotective properties is promising.



中文翻译:

Teucrium L. 属的物种作为具有抗菌、抗炎和辐射防护活性的活性药物物质的来源(综述)

总结了关于Teucrium L. (germander)属植物中次级代谢物复合物含量的文献数据,包括精油、酚类化合物(黄酮类化合物、环烯醚萜类化合物)、二萜类化合物和羟基肉桂酸。这些化合物的生物活性谱在正常条件下和各种病理状态下都有描述。确定主要质量指标和制定植物原料标准化方法的需要表明,进一步深入研究Teucrium物种是获得具有抗菌、抗微生物和辐射防护特性的新药的药物物质来源的前景。

更新日期:2021-08-19
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