Total Evaporation and Ion Integration technique (TE & II) was used for determination of the ⁶Li/⁷Li isotope ratio with the NaLiBO₂⁺ (m/z 71–73) and Na₂BO₂⁺ (m/z 88, 89) molecular ions emitted from the sodium lithium borate compound on the single filament assembly. Since the ion intensities are simultaneously collected by the multi-collector assembly and integrated till the sample is completely consumed, the measured ion intensity ratio ⁷²I/⁷³I is less affected by fractionation and hence closer to the true value. The fractionation profile for lithium isotopes showed concurrence with the Rayleigh's distillation law since the measured instantaneous ratio of ⁷²I/⁷³I at ∼63% sample consumption was equal to the integrated value at 100% sample consumption. The minimum sample size requirement for molecular ion method decreased to 50 ng of lithium for the TE method of data acquisition compared to 1–2 μg of lithium required for conventional method of limited scans. The relative standard deviation of ⁶Li/⁷Li ratio determined from the analyses of six samples of 500 ng each of the two natural Li₂CO₃ samples namely L-SVEC and high purity Spec-pure lithium was about 0.05% (1σ). Refractory materials Li₂TiO₃ and LiAlO₂ were also successfully analysed by the developed TE method with reduced sample size. The TE method enhanced the benefits of the molecular ion method by further decreasing the effect of fractionation as well as sample size requirement for accurate determination of ⁶Li/⁷Li ratio. The method could clearly distinguish between the two natural lithium samples, L-SVEC lithium and Spec pure lithium having a difference of 0.5% in their ⁶Li/⁷Li ratio.

总蒸发和离子积分技术 (TE & II) 用于测定⁶ Li/ ⁷ Li 同位素比，NaLiBO ₂ ⁺ ( m/z 71–73) 和 Na ₂ BO ₂ ⁺ ( m/z 88, 89 ) 从单丝组件上的硼酸锂钠化合物发出的分子离子。由于离子强度由多收集器组件同时收集并积分直到样品完全消耗，因此测得的离子强度比为⁷² I/ ⁷³I 受分馏的影响较小，因此更接近真实值。锂同位素的分馏曲线显示与瑞利蒸馏定律一致，因为在~63% 的样品消耗量下测得的⁷² I/ ⁷³ I 的瞬时比率等于在 100% 的样品消耗量下的积分值。与常规有限扫描方法所需的锂 1–2 μg 相比，分子离子方法的最小样品量要求降低至 50 ng 锂，而用于 TE 数据采集方法。⁶ Li/ ⁷ Li 比值的相对标准偏差，由对两种天然 Li ₂ CO ₃各 500 ng 的六个样品的分析确定样品即 L-SVEC 和高纯度 Spec-pure 锂约为 0.05% (1σ)。耐火材料 Li ₂ TiO ₃和 LiAlO ₂也通过开发的 TE 方法成功地进行了分析，并减少了样品尺寸。TE 方法通过进一步降低分馏的影响以及准确测定⁶ Li/ ⁷ Li 比率的样品大小要求，增强了分子离子方法的优势。该方法可以清楚地区分两种天然锂样品，即 L-SVEC 锂和 Spec 纯锂，其⁶ Li/ ⁷ Li 比率相差 0.5% 。