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Matrix stiffness primes cells for future oxidative stress
Trends in Cancer ( IF 14.3 ) Pub Date : 2021-08-18 , DOI: 10.1016/j.trecan.2021.08.003 Paul V Taufalele 1 , Cynthia A Reinhart-King 1
中文翻译:
基质刚度为细胞未来的氧化应激做好准备
更新日期:2021-09-21
Trends in Cancer ( IF 14.3 ) Pub Date : 2021-08-18 , DOI: 10.1016/j.trecan.2021.08.003 Paul V Taufalele 1 , Cynthia A Reinhart-King 1
Affiliation
Focus on metabolic reprogramming has re-emerged in recent years due to the far-reaching consequences of metabolism on nearly all cellular behaviors. In a recent study in Cell Metabolism, Tharp et al. show that adhesion-dependent mechanical signaling induces mitochondrial and metabolic reprogramming to help cells adapt to future oxidative stress.
中文翻译:
基质刚度为细胞未来的氧化应激做好准备
由于代谢对几乎所有细胞行为的深远影响,近年来重新关注代谢重编程。在最近的细胞代谢研究中,Tharp等人。表明粘附依赖性机械信号传导诱导线粒体和代谢重编程,以帮助细胞适应未来的氧化应激。