Pronounced weight loss was shown to improve adipocyte dysfunction and insulin sensitivity in obese subjects. While bariatric surgery is frequently accompanied by adverse side effects, weight loss due to caloric restriction is often followed by weight regain. Here we aimed to determine whether switching the diet from a metabolically harmful Western type diet to a balanced standard diet is sufficient to reverse adipocyte dysfunction in diet-induced obese mice.

中文翻译：

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改变饮食成分可以改善饮食诱导的肥胖小鼠的炎症，但不能改善脂肪细胞产热作用


显着的体重减轻被证明可以改善肥胖受试者的脂肪细胞功能障碍和胰岛素敏感性。虽然减肥手术经常伴随着不良副作用，但由于热量限制而导致的体重减轻往往会导致体重反弹。在这里，我们的目的是确定将饮食从对代谢有害的西方饮食转变为平衡的标准饮食是否足以逆转饮食引起的肥胖小鼠的脂肪细胞功能障碍。