Trisomy 21 has known associated clinical phenotypes, including skin and soft tissue concerns. However, the overall prevalence and types of findings are largely unclear.

中文翻译：

---

21 三体（唐氏综合征）患者的皮肤问题：梅奥诊所 22 年回顾性回顾

21 三体性已知相关的临床表型，包括皮肤和软组织问题。然而，总体流行率和发现的类型在很大程度上尚不清楚。