This article reviews the current status and challenges of using RF/microwave resonators for electron paramagnetic resonance (EPR) spectroscopy and imaging from the viewpoint of preclinical and clinical applications. In this review, resonator developments are summarized in the contexts of preclinical oximetry and free radical measurements in small rodents, clinical (human) oximetry, and human dosimetry. Guidelines for resonator development and optimization are also given for specific preclinical and clinical EPR applications.

中文翻译：

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用于临床前和临床 EPR 应用的射频/微波谐振器：现状和挑战

本文从临床前和临床应用的角度回顾了使用射频/微波谐振器进行电子顺磁共振 (EPR) 光谱和成像的现状和挑战。在这篇综述中，谐振器的发展在小型啮齿动物的临床前血氧饱和度和自由基测量、临床（人类）血氧饱和度测定和人体剂量测定的背景下进行了总结。还针对特定的临床前和临床 EPR 应用提供了谐振器开发和优化指南。