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Molecular mimicry between SARS-CoV-2 and the female reproductive system
American Journal of Reproductive Immunology ( IF 2.5 ) Pub Date : 2021-08-18 , DOI: 10.1111/aji.13494
Arad Dotan 1, 2 , Darja Kanduc 3 , Sylviane Muller 4, 5, 6, 7 , Alexander Makatsariya 8 , Yehuda Shoenfeld 1, 2, 9, 10
Affiliation  

Oogenesis, the process of egg production by the ovary, involves a complex differentiation program leading to the production of functional oocytes. This process comprises a sequential pathway of steps that are finely regulated. The question related to SARS-CoV-2 infection and fertility has been evoked for several reasons, including the mechanism of molecular mimicry, which may contribute to female infertility by leading to the generation of deleterious autoantibodies, possibly contributing to the onset of an autoimmune disease in infected patients.

中文翻译:

SARS-CoV-2 与女性生殖系统的分子模拟

卵子发生是卵巢产生卵子的过程,涉及一个复杂的分化程序,导致功能性卵母细胞的产生。该过程包括一系列经过精细调控的步骤。引发与 SARS-CoV-2 感染和生育有关的问题有几个原因,包括分子模拟机制,这可能通过导致有害自身抗体的产生而导致女性不育,可能导致自身免疫性疾病的发作在受感染的患者中。
更新日期:2021-08-18
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