Fly-over phylogeny across invertebrate to vertebrate: The giant panda and insects share a highly similar gut microbiota,Computational and Structural Biotechnology Journal

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Fly-over phylogeny across invertebrate to vertebrate: The giant panda and insects share a highly similar gut microbiota
Computational and Structural Biotechnology Journal ( IF 4.4 ) Pub Date : 2021-08-19 , DOI: 10.1016/j.csbj.2021.08.025
Ran Yao ₁ , Qinlong Dai _{2,

3} , Tonggui Wu ₄ , Zhisong Yang ₅ , Hua Chen ₆ , Guoqi Liu ₆ , Yudong Zhu _{2,

3} , Dunwu Qi ₇ , Xu Yang ₈ , Wei Luo _{2,

3} , Xiaodong Gu ₉ , Xuyu Yang ₉ , Lifeng Zhu ₁

Affiliation

Many studies highlight that host phylogeny and diet are the two main factors influencing the animal gut microbiota. However, the internal mechanisms driving the evolution of animal gut microbiota may be more complex and complicated than we previously realized. Here, based on a large-scale -analysis of animal gut microbiota (16 s RNA gene data from approximately 1,800 samples; 108 metagenomes) across a wide taxonomic range of hosts, from invertebrate to vertebrate, we found high similarity in the gut microbial community (high proportion of Gammaproteobacteria ()) of invertebrate insects and vertebrate bamboo-eating pandas (giant panda and red panda), which might be associated their plant-eating behavior and the presence of oxygen in the intestinal tract. A strain-level analysis using 108 metagenomes further revealed that the response to either host niches or selection by the host might further lead to host-specific strains (or sub-strains) among the different hosts congruent with their evolutionary history. In this study, we uncovered new insights into the current understanding of the evolution of animals and their gut microbiota.

中文翻译：

从无脊椎动物到脊椎动物的系统发育史：大熊猫和昆虫具有高度相似的肠道微生物群

许多研究强调宿主系统发育和饮食是影响动物肠道微生物群的两个主要因素。然而，驱动动物肠道微生物群进化的内部机制可能比我们之前意识到的更加复杂和复杂。在这里，基于对从无脊椎动物到脊椎动物等广泛分类宿主的动物肠道微生物群（来自约 1,800 个样本的 16 s RNA 基因数据；108 个宏基因组）的大规模分析，我们发现肠道微生物群落具有高度相似性无脊椎动物昆虫和脊椎动物食竹大熊猫（大熊猫和小熊猫）中存在高比例的伽马变形菌（Gammaproteobacteria），这可能与它们的食植物行为和肠道中存在氧气有关。使用 108 个宏基因组进行的菌株水平分析进一步表明，对宿主生态位或宿主选择的反应可能进一步导致不同宿主之间产生与其进化历史一致的宿主特异性菌株（或亚菌株）。在这项研究中，我们对当前对动物及其肠道微生物群进化的理解提出了新的见解。

更新日期：2021-08-19

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