A strategy to industrialize microwave synthesis from the perspectives of process optimization, scale up and reactor design was devised for the synthesis of glycerol carbonate (GC). The strategy is based on the application of absorbed energy density (AED) and absorbed power density (APD) parameters. Here, the microwave synthesis was conducted using a constant-power heating mode. The mapping of microwave heating characteristics based on heating power, reaction temperature and AED was first performed for the microwave system. Then, the optimization of APD and AED was conducted and the intensive optimum conditions at 175 J/g AED and 1.9 W/g APD was used to scale up the microwave synthesis from 0.3 mol (27 g) to 3 mol (267 g). The resulting syntheses were highly reproducible and consistent. Based on APD and AED, the thermal and non-thermal microwave effects can be characterized and they are useful in the design of continuous-flow microwave reactor.

从工艺优化、放大和反应器设计的角度设计了微波合成工业化的策略，用于合成碳酸甘油酯 (GC)。该策略基于吸收能量密度 (AED) 和吸收功率密度 (APD) 参数的应用。在这里，微波合成是使用恒功率加热模式进行的。首先对微波系统进行了基于加热功率、反应温度和 AED 的微波加热特性的映射。然后，进行了 APD 和 AED 的优化，并使用 175 J/g AED 和 1.9 W/g APD 的强化优化条件将微波合成从 0.3 mol (27 g) 放大到 3 mol (267 g)。由此产生的合成是高度可重复和一致的。基于APD和AED，