Fusobacterium nucleatum (F. nucleatum) is one of the most abundant Gram-negative anaerobic bacteria, part of the gut, and oral commensal flora, generally found in human dental plaque. Its presence could be associated with various human diseases, including, e.g., periodontal, angina, lung and gynecological abscesses. This bacteria can enter the blood circulation as a result of periodontal infection. It was proven that F. nucleatum migrates from its primary site of colonization in the oral cavity to other parts of the body. It could cause numerous diseases, including cancers. On the other hand, it was shown that Fusobacterium produces significant amounts of butyric acid, which is a great source of energy for colonocytes (anti-inflammatory cells). Therefore, it is very interesting to get to know the two faces of F. nucleatum.

具核梭杆菌 (F. nucleatum)是最丰富的革兰氏阴性厌氧菌之一，是肠道和口腔共生菌群的一部分，通常存在于人类牙菌斑中。它的存在可能与各种人类疾病有关，包括例如牙周、心绞痛、肺和妇科脓肿。由于牙周感染，这种细菌可以进入血液循环。事实证明，具核梭菌从其在口腔中的主要定植部位迁移到身体的其他部位。它可能导致多种疾病，包括癌症。另一方面，表明梭杆菌属产生大量丁酸，这是结肠细胞（抗炎细胞）的重要能量来源。因此，了解F. nucleatum 的两个面孔是非常有趣的。