To estimate attributable burden and costs of conditions associated with exposure to Adverse Childhood Experiences (ACEs) in Tennessee (TN) and Virginia (VA) during 2017. This is a cross-sectional study of individuals aged 18+ having exposure to ACEs using Behavioral Risk Factor Surveillance System (BRFSS) data. Eight chronic diseases (asthma, obesity, hypertension, diabetes, chronic obstructive pulmonary disease (COPD), depression, cardiovascular disease, and arthritis) and two risk factors (smoking and drinking) associated with ACEs were analyzed. Pearson's chi-square tests analyzed the association between ACEs, risk factors and chronic diseases. The population attributable risks (PAR) were estimated for the ACEs related diseases and risk factors and combined with health care expenses and Disability Adjusted-Life-Years (DALYs). Among those who experienced at least 1 ACE in TN, 10% had COPD, 17% had diabetes, 36% had obesity, and 30% had depression. Individuals who experienced at least 1 ACE in VA had higher percentages for COPD, obesity and depression diseases compared to those who had no ACE (p< .0001). ACEs’ exposure resulted in a burden of about 115,000 years and 127,000 years in terms of DALYs in TN and VA, respectively. The total health spending associated with ACEs based on PARs was about $647 million ($165 per adult) and $942 million ($292 per adult) in TN and VA respectively. The total costs associated with ACEs was about $15.5 billion ($3948) per person) and $20.2 billion ($6288 per person) in TN and VA, respectively. This study emphasizes the need to reduce ACEs due to high health and financial costs.

估计 2017 年在田纳西州 (TN) 和弗吉尼亚州 (VA) 与接触不良童年经历 (ACEs) 相关的条件的可归因负担和成本。这是一项使用行为风险对 18 岁以上接触 ACEs 的个人进行的横断面研究因素监视系统 (BRFSS) 数据。分析了与 ACE 相关的八种慢性疾病（哮喘、肥胖、高血压、糖尿病、慢性阻塞性肺病 (COPD)、抑郁症、心血管疾病和关节炎）和两种危险因素（吸烟和饮酒）。Pearson 的卡方检验分析了 ACE、风险因素和慢性疾病之间的关联。对 ACEs 相关疾病和风险因素的人群归因风险 (PAR) 进行了估计，并结合医疗保健费用和残疾调整生命年 (DALYs)。在 TN 中至少经历过 1 次 ACE 的患者中，10% 患有慢性阻塞性肺病，17% 患有糖尿病，36% 患有肥胖症，30% 患有抑郁症。与没有 ACE 的人相比，在 VA 中经历至少 1 次 ACE 的人患 COPD、肥胖和抑郁症的百分比更高（p < .0001)。ACEs 的暴露导致田纳西州和弗吉尼亚州的 DALY 分别为 115,000 年和 127,000 年。在田纳西州和弗吉尼亚州，基于 PAR 的与 ACE 相关的总卫生支出分别约为 6.47 亿美元（每位成人 165 美元）和 9.42 亿美元（每位成人 292 美元）。在田纳西州和弗吉尼亚州，与 ACE 相关的总成本分别约为每人 155 亿美元（3948 美元）和 202 亿美元（每人 6288 美元）。这项研究强调了由于高昂的健康和财务成本而需要减少 ACE。