Monitoring of Environmental Contaminants in Mixed-Use Watersheds Combining Targeted and Nontargeted Analysis with Passive Sampling,Environmental Toxicology and Chemistry

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Monitoring of Environmental Contaminants in Mixed-Use Watersheds Combining Targeted and Nontargeted Analysis with Passive Sampling
Environmental Toxicology and Chemistry ( IF 3.6 ) Pub Date : 2021-08-18 , DOI: 10.1002/etc.5192
Justin B Renaud ₁ , Lyne Sabourin ₁ , Shawn Hoogstra ₁ , Paul Helm ₂ , David R Lapen ₃ , Mark W Sumarah ₁

Affiliation

Understanding the environmental fate, transport, and occurrence of pesticides and pharmaceuticals in aquatic environments is of utmost concern to regulators. Traditionally, monitoring of environmental contaminants in surface water has consisted of liquid chromatography–tandem mass spectrometry analyses for a set of targeted compounds in discrete samples. These targeted approaches are limited by the fact that they only provide information on compounds within a target list present at the time and location of sampling. To address these limitations, there has been considerable interest in suspect screening and nontargeted analysis (NTA), which allow for the detection of all ionizable compounds in the sample with the added benefit of data archiving for retrospective mining. Even though NTA can detect a large number of contaminants, discrete samples only provide a snapshot perspective of the chemical disposition of an aquatic environment at the time of sampling, potentially missing episodic events. We evaluated two types of passive chemical samplers for nontargeted analysis in mixed-use watersheds. Nontargeted data were processed using MS-DIAL to screen against our in-house library and public databases of more than 1300 compounds. The data showed that polar organic chemicals integrative samplers (POCIS) were able to capture the largest number of analytes with better reproducibility than organic compound–diffusive gradients in thin film (o-DGT), resulting from the greater amount of binding sorbent. We also showed that NTA combined with passive sampling gives a more representative picture of the contaminants present at a given site and enhances the ability to identify the nature of point and nonpoint pollution sources and ecotoxicological impacts. Environ Toxicol Chem 2022;41:1131–1143. © 2021 Her Majesty the Queen in Right of Canada Environmental Toxicology and Chemistry © 2021 SETAC. Reproduced with the permission of the Minister of Agriculture and Agri-Food Canada.

中文翻译：

将目标和非目标分析与被动采样相结合，监测混合用途流域中的环境污染物

了解水生环境中农药和药物的环境归宿、运输和发生是监管机构最关心的问题。传统上，地表水中环境污染物的监测包括对离散样品中的一组目标化合物进行液相色谱-串联质谱分析。这些有针对性的方法受到以下事实的限制：它们仅提供有关在采样时间和位置存在的目标列表中的化合物的信息。为了解决这些限制，人们对可疑物筛查和非靶向分析 (NTA) 产生了相当大的兴趣，它可以检测样品中的所有可电离化合物，并为回顾性挖掘提供数据存档的额外好处。尽管 NTA 可以检测到大量的污染物，离散样本仅提供采样时水生环境化学处置的快照透视图，可能会丢失偶发事件。我们评估了两种类型的被动化学采样器，用于在混合用途流域进行非靶向分析。使用 MS-DIAL 处理非靶向数据，以筛选我们内部库和 1300 多种化合物的公共数据库。数据表明，与薄膜中的有机化合物扩散梯度 (o-DGT) 相比，极性有机化学品综合采样器 (POCIS) 能够以更好的重现性捕获最多数量的分析物，这是由于结合吸附剂的量更大。环境毒物化学2022；41:1131–1143。© 2021 加拿大女王陛下环境毒理学和化学 © 2021 SETAC。经加拿大农业和农业食品部部长许可转载。

更新日期：2021-08-18

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