The implants are increasingly being a part of modern medicine in various surgical procedures for functional or cosmetic purposes. The progressive use of implants is associated with increased infectious complications and prevention of such infections always remains precedence in the clinical settings. The preventive approaches include the systemic administration of antimicrobial agents before and after the surgical procedures as well as the local application of antibiotics. The relevant literature and existing clinical practices have highlighted the role of antimicrobial coating approaches in the prevention of implants associated infections, although the applications of these strategies are not yet standardized, and the clinical efficacy is not much clear. The adequate data from the randomized control trials is challenging because of the unavailability of a large sample size although it is compulsory in this context to assess the clinical efficacy of preemptive practices. This review compares the efficacy of preventive approaches and the prospects of antimicrobial-coated implants in preventing implant-related infections.

在出于功能或美容目的的各种外科手术中，植入物越来越多地成为现代医学的一部分。植入物的逐渐使用与感染并发症的增加有关，并且预防此类感染在临床环境中始终处于优先地位。预防方法包括手术前后全身应用抗菌药物以及局部应用抗生素。相关文献和现有临床实践都强调了抗菌涂层方法在预防植入物相关感染中的作用，尽管这些策略的应用尚未标准化，临床疗效也不是很清楚。由于无法获得大样本量，随机对照试验的足够数据具有挑战性，尽管在这种情况下必须评估先发制人的临床疗效。本综述比较了预防方法的有效性和抗菌涂层植入物在预防植入物相关感染方面的前景。