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Impaired myocardial work efficiency in heart failure with preserved ejection fraction
European Heart Journal - Cardiovascular Imaging ( IF 6.7 ) Pub Date : 2021-08-19 , DOI: 10.1093/ehjci/jeab153
Antonello D'Andrea 1, 2 , Federica Ilardi 3 , Flavio D'Ascenzi 4 , Francesco Bandera 5 , Giovanni Benfari 6 , Roberta Esposito 3 , Alessandro Malagoli 7 , Giulia Elena Mandoli 4 , Ciro Santoro 3 , Vincenzo Russo 1 , Michele D'Alto 1 , Matteo Cameli 4 ,
Affiliation  

Heart failure with preserved ejection fraction (HFpEF) is a growing public health problem. Impairment in left ventricular (LV) diastolic function has been proposed as a key pathophysiologic determinant. However, the role of concomitant systolic dysfunction despite preserved LV ejection fraction (LVEF) has not been well characterized. To analyse LV myocardial deformation, diastolic function, and contractile reserve (CR) in patients with HFpEF at rest and while during exercise, as well as their correlation with functional capacity.

中文翻译:

射血分数保留的心力衰竭患者的心肌工作效率受损

射血分数保留的心力衰竭 (HFpEF) 是一个日益严重的公共卫生问题。左心室 (LV) 舒张功能受损被认为是一个关键的病理生理决定因素。然而,尽管左心室射血分数 (LVEF) 保持不变,但伴随的收缩功能障碍的作用尚未得到很好的表征。分析 HFpEF 患者在休息和运动时的 LV 心肌变形、舒张功能和收缩储备 (CR),以及它们与功能能力的相关性。
更新日期:2021-10-21
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