This article is a part of a scientific project focused on obtaining a new type of composite materials that are characterized by singlet oxygen generation upon irradiation with red light, which can be used as antibacterial agents. The composite material is nanoscale graphite oxide (GO) particles covalently bonded to an axially substituted zirconium phthalocyanine complex. For this purpose, two phthalocyanine zirconium complexes, axially mono-substituted with 4-aminosalicylic or 4-aminophthalic acids, were prepared and measured in terms of structure, morphology, and spectroscopic properties. The zirconium phthalocyanines are photosensitizers, and the axial ligands are bridging links connecting the complexes to the GO carrier (due to their terminal amino groups and carboxyl groups, respectively). The axial ligand in zirconium phthalocyanine complexes has a strong influence on the stability and optical properties of composite materials and, consequently, on reactive oxygen species (ROS) generation. In this paper, the effect of composite components (4-aminophthalato or 4-aminosalicylato substituted zirconium phthalocyanine complex as a photosensitizer and graphite oxide as a carrier and modulator of the action of active components) on ROS generation for potential antibacterial use is discussed.

这篇文章是一个科学项目的一部分，该项目的重点是获得一种新型复合材料，其特征是在红光照射下产生单线态氧，可用作抗菌剂。该复合材料是纳米级氧化石墨 (GO) 颗粒与轴向取代的锆酞菁配合物共价键合。为此，制备了两种酞菁锆配合物，轴向单取代有 4-氨基水杨酸或 4-氨基邻苯二甲酸，并在结构、形态和光谱特性方面进行了测量。锆酞菁是光敏剂，轴向配体是将配合物连接到 GO 载体的桥连（分别由于它们的末端氨基和羧基）。锆酞菁配合物中的轴向配体对复合材料的稳定性和光学性能有很大影响，因此对活性氧 (ROS) 的产生有很大影响。在本文中，讨论了复合成分（4-氨基邻苯二甲酸酯或 4-氨基水杨酸取代的锆酞菁配合物作为光敏剂，氧化石墨作为载体和活性成分作用的调节剂）对潜在抗菌用途的 ROS 生成的影响。