X-rays Actuate Anticancer Drugs: Opening New Vistas in Prodrug Therapy,ChemBioChem

当前位置： X-MOL 学术 › ChemBioChem › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

X-rays Actuate Anticancer Drugs: Opening New Vistas in Prodrug Therapy
ChemBioChem ( IF 2.6 ) Pub Date : 2021-08-18 , DOI: 10.1002/cbic.202100373
Shreyas P Vaidya ₁ , Malay Patra ₁

Affiliation

The prodrug approach has emerged as a promising strategy for alleviating important limitations of small-molecule blockbuster chemotherapeutic drugs. Efficient and precise activation of a prodrug is the key for achieving the full potential of this strategy. Herein, we highlight the potential of X-rays for activating a prodrug locally in deep-seated tumors and point out its advantage over other activation triggers such as light.