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Distensibility of the ductus arteriosus in neonates and young infants undergoing transcatheter closure
Heart and Vessels ( IF 1.5 ) Pub Date : 2021-08-18 , DOI: 10.1007/s00380-021-01925-9
Kota Nagasawa 1 , Jun Muneuchi 1 , Yuichiro Sugitani 1 , Hiroki Ezaki 1 , Hirohito Doi 1 , Takashi Furuta 1 , Masaru Kobayashi 1 , Mamie Watanabe 1
Affiliation  

Device migration is one of serious complications in neonates and infants undergoing transcatheter closure of the patent ductus arteriosus (PDA). We hypothesize that neonates and young infants possess the distensibility of the ductus, which may be related to device migration. We retrospectively reviewed angiographic findings in 41 neonates and infants who underwent transcatheter closure of PDA. We measured diameters of the ductus at the pulmonary (PA) side, the center, and the aortic (AO) side before PDA closure, and the device center diameter after device closure. The distensibility index was defined as the ratio of the device center diameter after device deployment to the diameter at the center of the ductus before PDA closure. Age and weight at the procedure were 168 (117–260) days and 5.3 (4.3–6.9) kg, respectively. Thirty-seven subjects accomplished the successful device closure, and four subjects were declined because of the device instability or migration. Implanted devices included Amplatzer Duct Occluders in 33 subjects and Amplatzer Vascular Plug-2 in 8 subjects. The PDA diameters at PA side, at the center, AO side, and the device center diameter were 3.2 (2.2–4.3) mm, 4.7 (3.6–5.7) mm, 7.7 (6.3–9.4) mm, and 5.8 (4.2–6.9) mm, respectively. The PDA diameter before closure was not correlated age and weight. The distensibility index was 1.28 (1.06–1.64), which was significantly correlated to age (r = − 0.49, P = 0.001) and weight (r = − 0.53, P < 0.001). Infants with the younger age and the lower weight have the more distensible PDA, which may be a risk for device migration.



中文翻译:

接受经导管闭合术的新生儿和小婴儿的动脉导管扩张性

装置移位是接受经导管动脉导管未闭 (PDA) 闭合术的新生儿和婴儿的严重并发症之一。我们假设新生儿和小婴儿具有导管的扩张性,这可能与装置迁移有关。我们回顾性回顾了 41 名接受 PDA 经导管闭合术的新生儿和婴儿的血管造影结果。我们测量了 PDA 闭合前肺 (PA) 侧、中心和主动脉 (AO) 侧的导管直径,以及装置闭合后的装置中心直径。扩张性指数定义为装置展开后的装置中心直径与 PDA 闭合前导管中心直径的比值。手术时的年龄和体重分别为 168 (117-260) 天和 5.3 (4.3-6.9) 公斤。37 名受试者成功完成装置闭合,4 名受试者因装置不稳定或迁移而被拒绝。植入装置包括 33 名受试者的 Amplatzer 导管封堵器和 8 名受试者的 Amplatzer Vascular Plug-2。PA侧、中心、AO侧和设备中心直径的PDA直径分别为3.2(2.2-4.3)mm、4.7(3.6-5.7)mm、7.7(6.3-9.4)mm和5.8(4.2-6.9) ) 毫米,分别。闭合前PDA直径与年龄和体重无关。扩张指数为1.28(1.06-1.64),与年龄显着相关(在中心、AO 侧和器件中心直径分别为 3.2 (2.2-4.3) mm、4.7 (3.6-5.7) mm、7.7 (6.3-9.4) mm 和 5.8 (4.2-6.9) mm。闭合前PDA直径与年龄和体重无关。扩张指数为1.28(1.06-1.64),与年龄显着相关(在中心、AO 侧和器件中心直径分别为 3.2 (2.2-4.3) mm、4.7 (3.6-5.7) mm、7.7 (6.3-9.4) mm 和 5.8 (4.2-6.9) mm。闭合前PDA直径与年龄和体重无关。扩张指数为1.28(1.06-1.64),与年龄显着相关(r  = - 0.49, P  = 0.001) 和重量 ( r  = - 0.53, P  < 0.001)。年龄较小、体重较轻的婴儿具有更可扩张的PDA,这可能是设备迁移的风险。

更新日期:2021-08-18
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