当前位置: X-MOL 学术Clin. Orthop. Relat. Res. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Does Local Zoledronate Applied to Pasteurized Bone Autografts Improve the Likelihood of Union of Graft-host Junctions after Limb-sparing Surgery?
Clinical Orthopaedics and Related Research ( IF 4.2 ) Pub Date : 2021-08-18 , DOI: 10.1097/corr.0000000000001942
Piya Kiatisevi 1 , Bhasanan Sukanthanak 1 , Pongsiri Piakong 1 , Piyabuth Kittithamvongs 2
Affiliation  

Pasteurized bone autograft is a recycling biological reconstruction method for limb-sparing surgery when an allograft or other reconstruction technique is unavailable. Since the application of a local bisphosphonate to morselized allografts can reduce graft resorption and enhance bone formation without systemic complications, adding the local bisphosphonate to pasteurized bone autografts should reduce the graft resorption and improve the graft incorporation to host bone. However, no study that we know of has described the outcomes of local bisphosphonate application to massive allografts or pasteurized bone autografts. Thus, this study compared the outcomes of pasteurized bone autografts with and without local zoledronate.

中文翻译:

局部唑来膦酸应用于巴氏灭菌的自体骨移植物是否可以提高保肢手术后移植物-宿主连接的愈合可能性?

巴氏灭菌自体骨移植是一种回收生物重建方法,用于在同种异体移植或其他重建技术不可用时进行保肢手术。由于在颗粒状同种异体移植物中应用局部双膦酸盐可以减少移植物吸收并增强骨形成,而不会产生全身并发症,因此在巴氏灭菌的自体骨移植物中添加局部双膦酸盐应减少移植物吸收并改善移植物与宿主骨的融合。然而,据我们所知,还没有研究描述过局部双膦酸盐应用于大量同种异体移植物或巴氏灭菌自体骨移植物的结果。因此,本研究比较了使用和不使用局部唑来膦酸的巴氏灭菌自体骨移植物的结果。
更新日期:2021-08-18
down
wechat
bug