In this issue, Le et al. (2021. J. Cell Biol.https://doi.org/10.1083/jcb.202012114) describe a new role for the recently discovered protein CYRI in controlling the protrusions that allow cells to engulf extracellular fluid by macropinocytosis. This study helps explain how these structures are disassembled, but also uncovers a new mechanism linking the ability of cells to drink and their capacity for invasive migration.

中文翻译：

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CYRI 的动态 Rac1 抑制有助于细胞喝水，但阻止它们驾驶

在本期中，Le 等人。（2021. J. Cell Biol.https://doi.org/10.1083/jcb.202012114）描述了最近发现的蛋白质 CYRI 在控制突起方面的新作用，这些突起允许细胞通过巨胞饮作用吞噬细胞外液。这项研究有助于解释这些结构是如何分解的，而且还揭示了一种将细胞的饮水能力与其侵袭性迁移能力联系起来的新机制。