Background: Ameloblastoma is an odontogenic tumor occurring in jaws, with local aggressiveness and postoperative recurrence. This study was aim to investigate the clinical and radiographic risk factors for recurrence in ameloblastoma./nMethods: Patients diagnosed with ameloblastoma between March 2009 and March 2019 were retrospectively analyzed. Clinical and Radiological data and follow-up records were collected. Survival analyses were performed by Kaplan-Meier and log-rank tests, as well as Cox proportional hazards model./nResults: One hundred and fifty-eight patients (104 males and 54 females were enrolled. The overall recurrence rate for ameloblastoma was 13.29%, and 10.76% recurred within 5 years. Most of the tumors were located in mandible (86.71%), while the rest 21 cases were in maxilla (13.29%). More than half cases (55.06%) showed multilocular radiolucency, 61 cases (38.61%) showed unilocular radiolucency. Significant differences were found with amelobastoma recurrence rate related to treatment modality, impacted tooth and root resorption (P =0.002, 0.022 and 0.007 respectively)./nConclusions: Treatment modality, impacted tooth and root resorption all showed statistically significant associations with the recurrence rate in ameloblastoma. However, due to the limitation of this study, further studies are needed to reveal the true mechanism of ameloblastoma recurrence.

中文翻译：

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158例成釉细胞瘤复发危险因素回顾性研究

背景：成釉细胞瘤是一种发生在颌骨的牙源性肿瘤，具有局部侵袭性和术后复发。本研究旨在探讨成釉细胞瘤复发的临床和影像学危险因素。/n方法：回顾性分析 2009 年 3 月至 2019 年 3 月期间诊断为成釉细胞瘤的患者。收集临床和放射学数据和随访记录。通过 Kaplan-Meier 和对数秩检验以及 Cox 比例风险模型进行生存分析。/n结果：入组患者158例（男性104例，女性54例。成釉细胞瘤总体复发率为13.29%，5年内复发率为10.76%。大部分肿瘤位于下颌骨（86.71%），其余肿瘤位于下颌骨。上颌21例（13.29%），半数以上（55.06%）多房透亮，61例（38.61%）单房透亮。 （分别为 P = 0.002、0.022 和 0.007）。/n结论：治疗方式、阻生牙和牙根吸收都显示出与成釉细胞瘤复发率显着相关。然而，由于本研究的局限性，需要进一步的研究来揭示成釉细胞瘤复发的真正机制。