Self-organized protein patterns are of tremendous importance for biological decision-making processes. Protein patterns have been shown to identify the site of future cell division, establish cell polarity, and organize faithful DNA segregation. Intriguingly, several key concepts of pattern formation and regulation apply to a variety of different protein systems. Herein, we explore recent advances in the understanding of two prokaryotic pattern-forming systems: the MinCDE system, positioning the FtsZ ring precisely at the midcell, and the ParABS system, distributing newly synthesized DNA along with the cell. Despite differences in biological functionality, these two systems have remarkably similar molecular components, mechanisms, and strategies to achieve biological robustness.

中文翻译：

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自组织蛋白质模式：MinCDE 和 ParABS 系统。

自组织蛋白质模式对于生物决策过程非常重要。蛋白质模式已被证明可以识别未来细胞分裂的位点，建立细胞极性，并组织忠实的 DNA 分离。有趣的是，模式形成和调节的几个关键概念适用于各种不同的蛋白质系统。在此，我们探索了对两种原核模式形成系统的理解的最新进展：MinCDE 系统，将 FtsZ 环精确定位在中细胞，以及 ParABS 系统，将新合成的 DNA 与细胞一起分布。尽管生物功能存在差异，但这两个系统具有非常相似的分子成分、机制和实现生物稳健性的策略。