Flexible metal-organic frameworks (MOFs), renowned for their stimuli-responsive structures, are rising smart materials. With the recent progress in synthesizing MOFs with structural heterogeneity (i.e., containing multiple types of pores that exhibit distinctive geometries and functionalities), the targeted control of dynamics at the pore level has become a new direction of flexible MOF design. In this review, by introducing the recent advances of flexible MOFs, we discuss shifts in the research field from using the whole material to functionalizing individual pores and exploiting their relationships for cooperative dynamic behaviors and unprecedented properties. Some recent examples with pore-dependent dynamics are discussed to provide new perspectives for developing highly functional flexible MOFs. Finally, the latest progress in characterizing structural dynamics at the pore level is summarized with directions proposed for further development for a complete picture of the opportunities and challenges in this area.

以其刺激响应结构而闻名的柔性金属有机框架 (MOF) 正在成为新兴的智能材料。随着合成具有结构异质性的 MOFs（即含有多种类型的孔隙，表现出独特的几何形状和功能）的最新进展，在孔隙水平上有针对性地控制动力学已成为灵活 MOF 设计的新方向。在这篇综述中，通过介绍柔性 MOF 的最新进展，我们讨论了研究领域的转变，从使用整个材料到功能化单个孔，并利用它们之间的关系来实现协同动态行为和前所未有的特性。讨论了一些最近的具有孔隙相关动力学的例子，为开发高性能柔性 MOF 提供了新的视角。最后，