A new visible-light photocatalytic multicomponent reaction (MCR) involving N-alkyl-N-methylanilines, N-isocyanoiminotriphenylphosphorane, and carboxylic acids leading to 1,3,4-oxadiazole derivatives is reported. The developed mild reaction conditions enable a broad substrate scope and good functional group tolerance, as further highlighted in the late-stage functionalization of amino acids and drugs. Additionally, a two-step one-pot protocol for the synthesis of non-symmetrical diacylhydrazines is also reported.

中文翻译：

---

可见光光催化 Ugi/Aza-Wittig 级联到 2-Aminomethyl-1,3,4-oxadiazole 衍生物

报道了一种新的可见光光催化多组分反应 (MCR)，涉及 N-烷基-N-甲基苯胺、N-异氰基亚氨基三苯基正膦和羧酸，可生成 1,3,4-恶二唑衍生物。所开发的温和反应条件能够实现广泛的底物范围和良好的官能团耐受性，这在氨基酸和药物的后期官能化中得到进一步强调。此外，还报告了用于合成非对称二酰基肼的两步一锅法。