Recent achievements in triterpenoid semi-synthesis are discussed in this short review, which is divided into three parts according to the type of synthetic strategy being employed. These strategies include functionalization, modification of the carbon skeleton, and glycosylation. In the section on functionalization strategies, both functional group interconversions and new functional group installations on triterpenoid starting materials are described. The section on modification of the carbon skeleton is divided into three parts according to the tactic being applied, and incorporates rearrangement of the carbon skeleton, ring scission, and introduction of an additional heterocyclic ring. Meanwhile, in the section on glycosylation, notable achievements in the semi-synthesis of both natural and artificial triterpene saponins are discussed. Overall, the pivotal transformations that have brought about striking chemical structure variations of triterpenoid starting materials are highlighted herein, and it is hoped that this short review will provide inspiration to both established and new investigators engaged in this field of research. 1 Introduction2 Semi-Synthesis of Triterpenoids via Functionalization Strategies2.1 Functionalization of Rings with Functional Groups2.2 Functionalization of a Side Chain2.3 Functionalization of Rings without Existing Functional Groups 2.4 Functionalization of Angular Methyl Groups2.5 Functionalization of Angular Methyl Groups and Functional-Group-Free Rings2.6 Multisite Modifications3 Semi-Synthesis of Triterpenoids via C-Skeleton Modification Strategies3.1 Rearrangement Tactics3.2 Ring-Opening Tactics3.3 Additional Ring Introduction Tactics4 emi-Synthesis of Triterpenoids via a Glycosylation Strategy5 Conclusions and Outlook

中文翻译：

---

三萜类化合物半合成研究进展

在这篇简短的评论中讨论了三萜类半合成的最新成就，根据所采用的合成策略的类型将其分为三个部分。这些策略包括功能化、碳骨架修饰和糖基化。在官能化策略部分，描述了三萜类原料上的官能团相互转化和新官能团的安装。碳骨架的改性部分根据所应用的策略分为三个部分，包括碳骨架的重排、断环和引入额外的杂环。同时，在糖基化部分，讨论了天然和人工三萜皂苷半合成的显着成就。全面的，本文重点介绍了导致三萜类起始材料显着化学结构变化的关键转变，希望这篇简短的综述能够为从事该研究领域的既定研究人员和新研究人员提供灵感。1 介绍2 通过官能化策略半合成三萜类化合物2.1 具有官能团的环的官能化2.2 侧链的官能化2.3 不存在官能团的环的官能化2.4 角甲基的官能化2.5 角甲基和官能团的官能化无基团环2.6 多位点修饰3 通过C-骨架修饰策略半合成三萜类化合物3.1 重排策略3.2 开环策略3。