Women’s views on responsible motherhood influence decision-making regarding participation in prenatal screening. Previous studies showed that the probabilistic nature of the first-trimester combined test and the potential requirement for subsequent invasive diagnostics serve as legitimate reasons for women to exclude prenatal screening from their moral responsibilities. These moral barriers might now be less relevant with the introduction of the non-invasive prenatal test (NIPT) resulting in women feeling a moral duty to use NIPT screening as part of responsible motherhood. This qualitative study explores the impact of NIPT on women’s moral beliefs about the meaning of prenatal screening in relation to responsible motherhood. We performed semi-structured interviews with 29 pregnant women who were offered NIPT as a first-tier screening test within a Dutch nationwide study (TRIDENT-2). Results show that the inherent uncertainty about the fetus’s health despite improved accuracy and the lack of treatment for a detected disorder, combined with the possibility to obtain information about actionable anomalies through the fetal anomaly scan, support women’s perspectives that NIPT is not an obligation of responsible motherhood. Acceptance of NIPT is considered to be a free decision related to the information each woman needs to be a good mother for her child and her family. Women’s views may change when NIPT has expanded to include treatable or preventable conditions.

妇女对负责任母亲的看法会影响有关参与产前筛查的决策。先前的研究表明，妊娠早期联合检测的概率性质和随后侵入性诊断的潜在要求是女性将产前筛查排除在道德责任之外的正当理由。这些道德障碍现在可能与无创产前检查 (NIPT) 的引入不太相关，这导致女性感到有道德责任使用 NIPT 筛查作为负责任母亲的一部分。这项定性研究探讨了 NIPT 对女性关于产前筛查与负责任母亲的意义的道德信念的影响。我们对 29 名孕妇进行了半结构化访谈，她们在荷兰全国性研究 (TRIDENT-2) 中接受了 NIPT 作为一级筛查测试。结果表明，尽管准确性有所提高，但胎儿健康的内在不确定性以及对检测到的疾病缺乏治疗，再加上通过胎儿异常扫描获得可操作异常信息的可能性，支持女性的观点，即 NIPT 不是负责任的义务母性。接受 NIPT 被认为是一个自由决定，与每个妇女成为孩子和家人的好母亲所需的信息有关。当 NIPT 扩展到包括可治疗或可预防的疾病时，女性的观点可能会改变。结果表明，尽管准确性有所提高，但胎儿健康的内在不确定性以及对检测到的疾病缺乏治疗，再加上通过胎儿异常扫描获得可操作异常信息的可能性，支持女性的观点，即 NIPT 不是负责任的义务母性。接受 NIPT 被认为是一个自由决定，与每个妇女成为孩子和家人的好母亲所需的信息有关。当 NIPT 扩展到包括可治疗或可预防的疾病时，女性的观点可能会改变。结果表明，尽管准确性有所提高，但胎儿健康的内在不确定性以及对检测到的疾病缺乏治疗，再加上通过胎儿异常扫描获得可操作异常信息的可能性，支持女性的观点，即 NIPT 不是负责任的义务母性。接受 NIPT 被认为是一个自由决定，与每个妇女成为孩子和家人的好母亲所需的信息有关。当 NIPT 扩展到包括可治疗或可预防的疾病时，女性的观点可能会改变。接受 NIPT 被认为是一个自由决定，与每个妇女成为孩子和家人的好母亲所需的信息有关。当 NIPT 扩展到包括可治疗或可预防的疾病时，女性的观点可能会改变。接受 NIPT 被认为是一个自由决定，与每个妇女成为孩子和家人的好母亲所需的信息有关。当 NIPT 扩展到包括可治疗或可预防的疾病时，女性的观点可能会改变。