Introduction Cognitive impairments are prevalent in Huntington’s disease (HD), occurring many years prior to clinical diagnosis and are the most impactful on quality of life of patients. Cognitive interventions and exercise have been found to be efficacious in improving cognitive function in several clinical populations (e.g., older adults with mild cognitive impairment and dementia). However, the utility of cognitive interventions has not been systematically reviewed in HD. This systematic review aims to examine the efficacy of cognitive and physical interventions on cognitive function in HD.

中文翻译：

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亨廷顿病认知功能的认知导向治疗和体育锻炼：系统评价方案

简介认知障碍在亨廷顿舞蹈症 (HD) 中很普遍，发生在临床诊断前多年，对患者的生活质量影响最大。已发现认知干预和锻炼可有效改善若干临床人群的认知功能（例如，患有轻度认知障碍和痴呆症的老年人）。然而，认知干预的效用尚未在 HD 中进行系统审查。本系统评价旨在检查认知和身体干预对 HD 认知功能的有效性。