Hepatocellular carcinoma risk in hepatitis C stage-3 fibrosis after sustained virological response with direct-acting antivirals,Liver International

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Hepatocellular carcinoma risk in hepatitis C stage-3 fibrosis after sustained virological response with direct-acting antivirals
Liver International ( IF 6.0 ) Pub Date : 2021-08-15 , DOI: 10.1111/liv.15032
María Sánchez-Azofra ₁ , Inmaculada Fernández ₂ , María L García-Buey ₃ , Lourdes Domínguez-Domínguez _{4,

5} , Conrado M Fernández-Rodríguez ₆ , Antonio Mancebo ₇ , Lucía Bonet ₈ , Pablo Ryan ₉ , Francisco Gea ₁₀ , Antonio Díaz-Sánchez ₁₁ , Marian García-Mayor ₁₂ , Luz Martín-Carbonero ₁₃ , Pilar Castillo ₁ , María L Manzano ₂ , Leticia González-Moreno ₃ , Federico Pulido _{4,

5} , María L Gutiérrez ₆ , José M Moreno ₇ , Irene M García-Amengual ₈ , Guillermo Cuevas ₉ , Antonio Guerrero ₁₀ , Miguel Rivero-Fernández ₁₁ , María E Portales ₁₂ , María L Montes ₁₃ , Antonio Olveira ₁

Affiliation

Gastroenterology Department, La Paz University Hospital, Madrid, Spain.
Gastroenterology Department, 12 de Octubre University Hospital, Madrid, Spain.
Gastroenterology Department, La Princesa University Hospital, Madrid, Spain.
HIV Unit, Internal Medicine Department, 12 de Octubre University Hospital, Madrid, Spain.
Instituto de Investigación Sanitaria Hospital, Madrid, Spain.
Gastroenterology Department, Hospital Universitario Fundación Alcorcón, University Rey Juan Carlos, Madrid, Spain.
Gastroenterology Department, Albacete University Hospital, Albacete, Spain.
Gastroenterology Department, Son Espases University Hospital, Palma de Mallorca, Spain.
HIV Unit, Internal Medicine Department, Infanta Leonor University Hospital, Madrid, Spain.
Gastroenterology Department, Ramón y Cajal University Hospital, Madrid, Spain.
Gastroenterology Department, Sureste University Hospital, Arganda del Rey, Spain.
Gastroenterology Department, Hospital Central de la Defensa Gómez Ulla, Madrid, Spain.
HIV Unit, Internal Medicine Department, La Paz University Hospital, Madrid, Spain.

Patients with chronic hepatitis C and stage 3 fibrosis are thought to remain at risk of hepatocellular carcinoma after sustained virological response. We investigated this risk in a large cohort of patients with well-defined stage 3 fibrosis.

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