Branched-chain amino acids (BCAA) are often emphasized in the diets of avid exercisers, yet population data demonstrates a correlation between circulating BCAA and insulin resistance. However, it is unclear if BCAA independently promote insulin resistance in otherwise healthy cells. The purpose of this study is to examine the effect of a BCAA mixture on muscle insulin signaling in vitro in both insulin resistant and sensitive cells.

中文翻译：

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超生理而非生理水平的支链氨基酸降低肌管胰岛素敏感性

支链氨基酸 (BCAA) 在狂热锻炼者的饮食中经常被强调，但人口数据表明循环 BCAA 与胰岛素抵抗之间存在相关性。然而，目前尚不清楚 BCAA 是否独立促进其他健康细胞的胰岛素抵抗。本研究的目的是检查 BCAA 混合物对胰岛素抵抗和敏感细胞体外肌肉胰岛素信号传导的影响。