Impact of Multimeric Ferrocene-containing Cyclodecapeptide Scaffold on Host-Guest Interactions at a β-Cyclodextrin Covered Surface,ChemPhysChem

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Impact of Multimeric Ferrocene-containing Cyclodecapeptide Scaffold on Host-Guest Interactions at a β-Cyclodextrin Covered Surface
ChemPhysChem ( IF 2.3 ) Pub Date : 2021-08-16 , DOI: 10.1002/cphc.202100469
Enrique Sanchez Perez ₁ , Ritu Toor ₁ , Pierrick Bruyat ₁ , Céline Cepeda ₁ , Mélissa Degardin ₁ , Jérôme Dejeu ₁ , Didier Boturyn ₁ , Liliane Coche-Guérente ₁

Affiliation

Host-guest interaction is a promising way of attaching biomolecules to solid surfaces since the binding strength is tunable by the nature of host and guest partners or through the interaction valency. Herein, the effect of multivalency based cyclodecapeptide scaffold on the host-guest interaction strength is reported. The gradual increase of the guest valency improves the stability of the inclusion complex drastically.

中文翻译：

含多聚二茂铁的环十肽支架对 β-环糊精覆盖表面的主客体相互作用的影响

主客体相互作用是将生物分子连接到固体表面的一种很有前途的方式，因为结合强度可以通过主客体的性质或通过相互作用价进行调节。在此，报告了基于多价的环十肽支架对主客体相互作用强度的影响。客体化合价的逐渐增加显着提高了包合物的稳定性。

更新日期：2021-08-16

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