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Are biventricular and biatrial function truly preserved after arterial switch operation?
Heart ( IF 5.7 ) Pub Date : 2021-10-01 , DOI: 10.1136/heartjnl-2021-319820
Ellen Ostenfeld 1 , Marcus Carlsson 2, 3
Affiliation  

Arterial switch operation is currently the standard procedure when correcting for transposition of the great arteries (TGA) with a good longevity of the intervention.1 While aortic and coronary artery complications as well as mortality are low, right-sided lesions such as right ventricular (RV) outflow and neopulmonary valve dysfunction may occur and require reintervention.2 Patients undergoing cardiac reinterventions in childhood are more likely to have residual lesions and have a higher risk of valvular and ventricular dysfunction as well as arrhythmia.3 In TGA, left ventricular (LV) function is reported normal at long-term follow-up,4 5 but RV dysfunction is present at mid-term after arterial switch operation.6 Systemic ventricular function has been suggested as a prognostic marker of outcome in TGA after atrial switch and in congenital corrected TGA.7 Even if echocardiography is the first-line imaging modality for cardiovascular evaluation of patients with congenital heart disease, cardiac magnetic resonance (CMR) is considered gold standard for ventricular and atrial volumes and function owing to high accuracy, precision and reproducibility.8 As most studies of patients with TGA and arterial switch operation are small cohorts presenting either on a ventricular or atrial functional results, whole heart assessment including all four cardiac chambers in a comprehensive manner has been lacking. A larger population of patients with TGA and arterial switch operation also allows a meaningful investigation of whether any ventricular and atrial functional alterations could be caused by differences in simple and complex TGA morphology or by usual and …

中文翻译:

动脉转换手术后双心室和双心房功能是否真正得到保留?

动脉转换手术是目前矫正大动脉 (TGA) 转位的标准程序,干预时间长。 1 虽然主动脉和冠状动脉并发症以及死亡率很低,但右侧病变,如右心室 ( RV) 流出道和新肺动脉瓣功能障碍可能发生并需要再次介入治疗。2 儿童期接受心脏再介入治疗的患者更可能有残留病灶,瓣膜和心室功能障碍以及心律失常的风险更高。 3 在 TGA 中,左心室 (LV ) 功能在长期随访中报告正常,4 5 但在动脉转换手术后中期出现 RV 功能障碍。6 系统性心室功能已被建议作为心房转换后 TGA 和先天性矫正 TGA 结局的预后标志物。7 即使超声心动图是先天性心脏病患者心血管评估的一线成像方式,心脏磁共振 (CMR) ) 被认为是心室和心房容积和功能的金标准,因为它具有高精度、精密度和可重复性。8 由于大多数 TGA 和动脉开关手术患者的研究都是小队列,呈现心室或心房功能结果,全心评估包括一直缺乏全面的所有四个心腔。更多的 TGA 和动脉开关手术患者也可以进行有意义的调查,以确定任何心室和心房功能的改变是否可能由简单和复杂的 TGA 形态的差异或由通常和……
更新日期:2021-09-24
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